14 Best Medical-Grade Skincare Brands You Can Get In Singapore

Dermatologist-approved picks

Looking to boost your skincare routine? You should definitely check out medical-grade skincare brands available in Singapore. These types of skincare products are specially formulated to address specific concerns and usually contain a more concentrated version of active ingredients that are clinically proven to be effective.

How to get medical-grade skincare

Ready to shop? Not so fast! While there are medical-grade skincare brands that can be purchased easily, some are only available in aesthetic clinics, and a consultation to see if a particular medical-grade product is suitable for your skin and a prescription by a dermatologist is needed. These items are also a bit more expensive so it’s best to see what your options are before deciding on which one to invest in. Ahead, medical-grade skincare brands you can get in Singapore.

1. Skinceuticals

Skincare bottles with dropper

Skinceutical's bestsellers. (Photo from: @skinceuticals)

Skinceuticals boasts highly efficient formulas that are used by dermatologists and plastic surgeons to address signs of ageing and promote healthy skin. Its antioxidant-packed skincare products are the result of breakthroughs in skin cancer research.

Product/s To Check Out: Most of their products have gained holy grail status, most specifically the CE Ferulic (a vitamin C serum famous for fading dark spots) and the Triple Lipid Restore 2:4:2 (an anti-ageing cream with ceramides, natural cholesterol, and fatty acids).

You can get the CE Ferulic for SGD285 per 30ML here and Triple Lipid Restore 2:4:2 for SGD285 per 48ML here. Both are available at Skinceuticals Singapore website.

2. Obagi Skincare

White skincare bottle

Obagi Skincare is famed for its acne control products. (Photo from: @obagimedical)

Obagi Medical is best known for its medical-grade acne solution products containing benzoyl peroxide and salicylic acid such as the CLENZIderm M.D.® Acne Therapeutic System which is available in Singapore. It’s a three-step method that is touted to be clinically proven to treat acne.

Product/s To Check Out: Another coveted product from the brand is the prescription-only Obagi Tretinoin Cream for treating acne vulgaris.

You can get the Obagi CLENZIderm MD Pore Therapy on Feel Beautiful Singapore's website for SGD64 per 148ML. No price is available for Obagi Tretinoin Cream as the dosage depends per patient.

3. Dr. Dennis Gross

Peel pads on a wooden background

The brand's bestselling Alpha Beta® Universal Daily Peel is sold every three seconds. (Photo from: @drdennisgross)

Dr. Dennis Gross is perhaps one of the best known medical-grade skincare that you can buy in Singapore. Did you know that their bestselling Alpha Beta® Universal Daily Peel is sold every three seconds, according to the brand? Many swear by its two-step AHA/BHA peel which promises to combat uneven skin tone and texture.

Product/s To Check Out: Aside from this chemical exfoliator, other hyped Dr. Dennis Gross products include the Spectralite Faceware Pro and the relatively new Advanced Retinol + Ferulic Intense Wrinkle Cream

You can get the Alpha Beta® Universal Daily Peel for SGD155 per 30 treatments here, the Spectralite Faceware Pro at SGD785 here, and the Advanced Retinol + Ferulic Intense Wrinkle Cream at SGD129 per 60ML here. These are all available at Sephora Singapore.

4. IDS Skincare

Skincare in white bottles and metallic caps

The award-winning C-Plus serum is a must-try from the brand. (Photo from: @idsskincare)

Love local? Browse the skincare selections from IDS Skincare. The brand is founded by well-renowned dermatologist Dr. SK Tan and is created based on his 20 years of experience in the industry. But before you buy anything from IDS Skincare’s site, it’s best to book a consultation first to know which products suit your skin best.

Product/s To Check Out: Its award-winning C-Plus serum has garnered praises ability to reduce fine lines and wrinkles effectively.

You can find this product on IDS Skincare's website for SGD163.50 per 30ML.

5. 111SKIN

Cream in a glass jar

111SKIN has many celebrity fans. (Photo from: @111skin)

Loved by the likes of Margot Robbie and Kim Kardashian, 111SKIN is certainly a coveted brand. It’s best known for its high-quality skincare products that are made from unique ingredients. One even has real diamonds in it!

Product/s To Check Out: The intense moisturiser 111SKIN Celestial Black Diamond Cream uses black diamond particles to help active ingredients penetrate deeply for faster and better results. Who doesn’t want to shine like a diamond?

You can find this product on Net-A-Porter for SGD1,326 per 50ML.

6. Skinbetter Science®

Skincare in blue bottles with metallic cap

The brand boasts a range of fuss-free medical-grade products. (Photo from: @skinbetter)

Skinbetter Science® is recognised for its development of fuss-free medical-grade products that work. The brand is made by a group of aesthetic experts with years of experience. It has produced a variety of skincare items, from serums to neck creams.

Product/s To Check Out: You may just find your next holy-grail in their AlphaRet Overnight Cream, a fragrance-free cream that features retinoid combined with an alpha hydroxy acid (AHA) to create a super potent exfoliator that will deliver glowing results “with little-to-no irritation”.

You can find this product on Freia247's website for SGD194 per 30ML.

7. Dr. TWL Dermaceuticals

Eye cream with green packaging

The Elixir-V™ Anti-Wrinkle Eye Cream For Face is claimed to be a botox alternative. (Photo from: drtwlderma.com)

Dr. TWL Dermaceuticals is a line of skincare products that are formulated by Dr. Teo Wan Lin. The brand doesn't just produce medical-grade serums, eye creams and cleansers but also skincare gadgets and fabric suited for sensitive skin.

Product/s To Check Out: One of the brand's famous products is the Elixir-V™ Anti-Wrinkle Eye Cream For Face which, true to its name, can be used for both the face and the skin around the eye area. Dr. TWL Dermaceutical claims that it's a good botox alternative for addressing frown lines, bunny lines and crow’s feet.

You can find this product on Dr. TWL Dermaceuticals' website, sold as a set for SGD360.

8. EltaMD

Sunscreen in a stick

EltaMD is known for its medical-grade sunscreens. (Photo from: @eltamdskincare)

Looking for a new sunscreen? Try EltaMD’s medical-grade quality sunscreen. These sunscreens are specially formulated for anyone who has rosacea, acne-prone skin or those with uneven skin tones. They can also be layered with makeup thanks to their oil-free formulas.

Product/s To Check Out: For go-getters, the best choice is the ELTAMD - UV Sport Water-Resistant Full-Body Sunscreen SPF 50 which has a broad-spectrum UVA/UVB sun protection and is rich in antioxidants that combat free radicals.

You can find this product on Zalora Singapore's website for SGD74.90 per 198g.

9. Murad

Skincare with orange background

Murad has been producing great skincare products since 1989. (Photo from: @muradskincare)

Another popular medical-grade skincare brand that you can buy over the counter in Singapore is Murad. This high-end beauty label has produced countless top-notch products since its founding in 1989 and continues to produce hype-worthy skincare items to this day. 

Product/s To Check Out: One popular product from Murad is the Rapid Dark Spot Correcting Serum that’s designed to reduce dark spots and hyperpigmentation quickly — perfect for achieving flawless skin, stat!

You can find this product on Harrods Singapore's website for SGD124 per 30ML. 

10. Dr. Barbara Sturm

Skincare in slightly transparent bottle with dropper

Dr. Barbara Sturm is popular among skincare enthusiasts. (Photo from: @drbarbarasturm)

Dr. Barbara Sturm is popular among skincare enthusiasts and high-profile influencers like Hailey Bieber — and it’s not just hype! The Hyaluronic Serum is very much beloved for its low molecular weight, meaning it won’t just sit on top of your skin and can penetrate into the deeper layers for optimal hydration.

Product/s To Check Out: Their bestseller isn’t just the only product worthy of buzz. Dr. Barbara Sturm also has premium hair care offerings such as the Anti-Hair Fall Collection that works as well.

You can get the Dr. Barbara Sturm Hyaluronic Serum for SGD515 per 30ML here, the Dr. Barbara Sturm Anti-Hair Fall Shampoo at SGD100 per 250ML here, and the Dr. Barbara Sturm Anti-Hair Fall Repair Mask at SGD110 per 95ML here. These are all available on Dr. Barbara Sturm Singapore's website.

11. CNP Laboratory

ICYDK, this skincare brand is actually the brainchild of 50 Korean dermatologists at the CNP Skin Clinic based in Seoul who wanted to provide good after-treatment home care to address their clients' skin issues. Nowadays, it's beloved by K-celebs like soloist BoA and Girls' Generation's Yuri who are known for their flawless visuals.

Product/s To Check Out: The antioxidant-rich and hydrating Propolis Energy Ampule comes highly recommended by BoA, who mixes it with her base products to achieve her dewy, glowing skin.

You can get the Propolis Energy Ampule through the Guardian. It's priced at SGD29.15 per 15ML.

12. Perricone MD

Fast-absorbing, oil-free, tinted moisturizer with SPF. (Photo from: pericconemd.com)

Why settle for the ordinary when you can have the extraordinary? Perricone MD promises not just results but a transformation, fueled by rigorous science and the purest ingredients. It's not merely skincare; it's about glowing from within.

Product/s To Check Out. Think of it as your skin's best friend—luxuriously rose-scented and deeply hydrating.

You can find this product on LookFantastic’s website, priced at SGD98 per 30ML.

13. MACRENE Actives

Delivers a boost in hydration and plumpness that will last all day. (Photo from: net-a-porter.com)

MACRENE Actives is the brainchild of Dr. Macrene Alexiades – a titan in the dermatology field. This brand is her vision brought to life, aiming to swap out invasive procedures for skincare steeped in potent active ingredients, derived from the healing powers of botanicals and life from the sea.

Product/s To Check Out: MACRENE Actives' High Performance Face Serum. This isn't just a serum; it's a multi-tasking marvel ready to overhaul your skin game.

You can get it at NET-A-PORTER's website for SGD168 per 15ML.

Which medical-grade skincare will you be exploring?

(Cover photo from: @drbarbarasturm)

This article was first published on 6 March 2023. Last updated: 8 March 2024.

Next, discover the best moisturisers for Singapore weather.

Comments, questions or feedback? Email us at [email protected].

Related Articles